Fatal acute liver failure after intravenous amiodarone administration
نویسندگان
چکیده
منابع مشابه
Fatal Acute Liver Failure With Intravenous Amiodarone: A Case Report and Literature Review
Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of h...
متن کاملAcute Liver and Renal Failure: A Rare Adverse Effect Exclusive to Intravenous form of Amiodarone
Amiodarone is an antiarrhythmic drug which is highly effective against a wide spectrum of ventricular tachyarrhythmias making it irreplaceable in certain group of patients. We report an unusual case of acute liver and renal failure within 24 hours of initiation of intravenous (IV) amiodarone which resolved after stopping the medication. The mechanism of acute liver and renal toxicity is not cle...
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Liver cell regeneration was assessed by determining the mitotic index and the frequency of liver cells with interploid DNA values in livers from patients dying from fulminant hepatitis. For comparison, the same parameters were determined in patients with uncomplicated hepatitis. We found comparable levels of regeneration in the two groups, indicating that the rate of liver cell destruction is a...
متن کاملPredictors of intravenous amiodarone induced liver injury
Background Intravenous (IV) amiodarone may be associated with liver injury that may necessitate drug discontinuation. The prediction of amiodarone induced liver injury (AILI) and its severity may help careful patient monitoring or the choice of other measures alternative to amiodarone in high risk patients. Little is known regarding predictors of AILI. Objectives To address the predictors of ...
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During a randomized, double blind, crossover, placebo-controlled clinical trial of oral isoniazid (isonicotonic acid hydrazide, INH),’ serum cholesterol was measured during the sixth week of treatment ofboth phases ofplaeebo and the drug in five men. The ages of the patients ranged from 28 to 65 years, with a mean of 45 years. The dosage of isoniazid was 300 mg thrice daily (15 mg/kg body weigh...
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ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2015
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2013.07.011